ABSTRACT Background: Hypertension is closely related to impaired endothelial dependent vasodilation due to decreasing availability of blood nitric oxide (NO) and high fat intake. Objective: To analyze blood NO and fat intake differences in patients with hypertension and non hypertension. Method: The study was a cross-sectional design and sampling was carried out in Sidoarjo District Ho…
Abstract Objectives: To determine the factors that may be used as the prog¬nostic parameter for the therapeutic efficacy of neoadjuvant chemo¬therapy, which can be used to revising the management of early stage cervical cancer patients with large lesions. Methods: This was a retrospective cohort study. The study was con¬ducted in the Dr. Cipto Mangunkusumo Hospital, Faculty of Medi¬cine…
Abstract Objective: To understand the molecular profile by identifying the mutation of KRAS and BRAF in borderline type ovarian tumor. Method: In the study, we examined paraffin tissue sample from De¬partment of Pathology Anatomy, University of Indonesia/Dr. Cipto Mangunkususmo Hospital, Jakarta, that was diagnosed as borderline epithelial ovarian tumor. Seventeen samples were taken to San…
The research of synthesize and quantitative structure activity relationship of benzoy1 salicylic acid derivatives for analgesic activity in mice had been done by Soekardjo et al. (2009). From the fourteen compounds that had been synthesized, it has been known that 0-(3-chlorometilbenzoyl) salicylic acid had the best analgesic activity (ED50 value was 15.73% mg/kg) while the ED50 value of acetyl…
Piperacillin has antimicrobial action but it is not absorbed from gastrointestinal tract Therefore, it needs structure modification to increase its absorption while keeping its antimicrobial action. The 4-methy/piperazin¬N-carbonyl ampicillin was the product of reaction between ampicillin and 4-methylpiperazin-N-carbonyl chloride using Schotten Baumann method. The aim of this research was to c…
Objective: To find out the diagnostic value of CA125 and HE4 as a tumor marker, and also RM1 and ROMA as a malignancy predictor in patients with ovarian tumors. Methods: This study was a diagnostic study using cross-sectional design.This study was performed in Jakarta from November 2010 to May 2011. One hundred and twenty eight serum samples of patients diagnosed with ovarian tumors were col…
Perioperative management on patients undergoing pituitary surgery is varies according to the size of pituitary lesion, type of lesion, surgical method used and the ideal preoperative function of endocrine. Specific problems in most patients relate to primary hormonal hypersecretion conditions and its complications. It cause by the absence of best methods for all patients undergoing this kind o…
Abstract Traumatic Brain Injury (TBI) is a big problem in the world because of high mortality and morbidity. TBI burdens approximately 600,000 people every year in USA. Head injuries are found in 17.6% of all trauma in-patients and are the most common cause of death after injury (26.6%) in Germany. Here we report anesthetic management in male, 19 yrs old, 65 kgs body wieght, diagnose was Epid…
Anesthesia procedure in the prone position was often necessary in order to facilitate access to a variety of surgical operations, including neurosurgery among others, the spine surgery. In addition to physiological changes, some complications can also occur in the prone position that should receive special attention, so it requires a good understanding of this issue. Case: Laminectomy was bein…