Areca (Areca catechu L.) seeds ethanolic extract shows cytotoxic activity against MCF-7 cells. The aim of this research is to examine the cytotoxic effect, apoptosis induction andtarget on bcl-2 expression in MCF-7 cells of A. catechu chloroform fraction (ACF). The A. catechu seed powders were extracted by using ethanol 96%. Then, the extract was fractioned with partition by hexane, chloroform,…