Bruguiera gymnorhiza is one of the mangrove plant that has not been widely studi ed as a potential anti cancer. Previous research has suggested that the methanol extract of stem bark of B. gymnorhiza was cytotoxic against HeLa cells. The purpose ofthis study was to determine the cytotoxic effect and llPoptosis induction of chloroform fraction from the stem bark of B. gymnorhiza on HeLa cells.…
Bruguiera gymnorhiza is one of the mangrove plant that has not been widely studied as a potential anticancer. Previous research has suggested that the methanol extract of stem bark of B. gymnorhiza was cytotoxic against HeLa cells. The purpose ofthis study was to determine the cytotoxic effect and apoptosis induction of chloroform fraction from the stem bark of B. gymnorhiza on HeLa cells. The …
Isolasi and identifikasi of kaempferol from jangkang (Homalociadium platycladum (F. Muell) Bailey) leaves and its activity against B. Subtilis ATCC 9466 dan styphi ATCC done. The dried graund leaves (300.04 gram) were macerated with petroleum ether, choroform and methanol respectively. The methol extract was the most active extract against both bacteria. Further separations of this extract usin…
Hesperidin, a flavonoid, shows strong cytotoxic effect in several cancer cell lines. The aim of this research was to investigate cytotoxic activities of hesperidin alone and in combination with doxorubicin. Cell viability assay of hesperidin, doxorubicin, and combination treatments were carried out by using 11 MTT assay. Apoptosis assay was done using double staining method using Ethidium Brom…
Abstract: Doxorubicin is one of the standard regiment for breast cancer chemotherapy, but resistance to this agent is often occured and long period usage will induce cardiotoxicity. Therefore, combination therapy (eo-chemotherapy) is needed to improve the efficacy of doxorubicin and to reduce its systemic toxicity. Naringenin is one of the most abundant flavonoids in citrus fruits which showed …
Areca (Areca catechu L.) seeds ethanolic extract shows cytotoxic activity against MCF-7 cells. The aim of this research is to examine the cytotoxic effect, apoptosis induction andtarget on bcl-2 expression in MCF-7 cells of A. catechu chloroform fraction (ACF). The A. catechu seed powders were extracted by using ethanol 96%. Then, the extract was fractioned with partition by hexane, chloroform,…