Iodine severe deficiency is a major cause of impairment due to iodine deficiency disorders. Cretinism is a consequence of iodine deficiency in the womb with clinical signs that stand out among others is mental retardation. In Indonesia, there were many cases of endemic goiter and cretinism. Diagnosis of cretinism can be established more accurately by laboratory tests, but it is expensive and le…
Iodine Deficiency Disorders (IDD) was associated with female reproductive hormones disorders. Hypothyroidism inhibits follicular development which subsequently inhibited estrogen secretion. Biosynthesis of estrogen derived from testosterone through aromatization mechanism in ovarian granulose cells. This study aimed to determine changes in levels of serum testosterone and estrogen in hypothy…
A 24-year-old woman was admitted with general weakness, umbilical swelling, developmental delay, speech disorder, constipation, gait problem. Her findings were umbilical hernia, xerosis, dry hair, and short stature. After thyroxine treatment, she also had headache, vomiting, and palpitation, lack of appetite, and sleep disturbance. Pituitary magnetic resonance imaging revealed a heterogeneous m…
Clinical management for children with developmental disorder, including laser puncture, medical treatment, nutrition, psychological counseling, or physiotherapy, had been instigate by BP2GAKI. There was no previous research on evaluating the long term outcome of children growth and development who had completed the clinical management in BP2GAKI. Objectives of this study are to investigated the…
Background: Hypothyroidism in women at childbearing age (WCA) will cause reproduction disorder, i.e. infertility, spontaneous abortion, impaired growth and development of foetus, placental abruption, and preterm delivery. Pesticide exposure is suspected to cause hypothyroidism. The research objective is to prove that pesticide exposure is a risk factor for hypothyroidism among WCA in agricultur…
Pregnant women with iodine dejicienct have risk of miscarriages, stillbirth to congenital in newborn in the form of neuro-developmental dis 0 rders, mental and physic. One effort that can be done to detect cas es of Iodine Dejiciency Disorders (IDD) at early stage is to conduct newborn screening for hypothyroidism. In Indonesia, this screening program has not become anational mandatory program.…
Hypothyroidism among women 0/ childbearing age (WCA) in the agricultural area: A study in Kersana sub-district Brebes regency Background: Hypothyroidism can cause infertility, spontaneous abortion. fetal growth-development disorders, Placental abruption and prematurity. Exposure to pesticides, both of organochlorines and organophosphate, can cause hypothyroidism. The aim 0/ the study was to exa…