Pengaruh Propylthiuouracil terhadap Kadar Testosteron dan Estrogen pada Tikus…

Iodine Deficiency Disorders (IDD) was associated with female reproductive hormones disorders. Hypothyroidism inhibits follicular development which subsequently inhibited estrogen secretion. Biosynthesis of estrogen derived from testosterone through aromatization mechanism in ovarian granulose cells. This study aimed to determine changes in levels of serum testosterone and estrogen in hypothy…

Pengaruh Iodium terhadap Perubahan Fungsi Tiroid dan Status Iodium/

Iodine is an essential element that enables the thyroid gland to produce thyroid hormones. The source of iodine in the body comes from food, iodized salt and iodine capsules. Iodized salt and iodine capsules had been used by the government in Iodine Deficiency Disorders (IDD) elimination program. However, iodine capsules prophylaxis program in the IDD endemic areas had caused symptoms of hypert…

Sasaran Aksi Pentagamavunon-O pada Steroidogenesis Sc! Luteal Melalui Penguku…

Introduction: Pentagamayunon-0 (PG V-0) compound, a curcurnin analog, can inhibit steroido¬genesis of luteal cell culture by inhibiting the production ofprogesterone. The action site of PG V¬0 on steroidogenesis of luteal cells is still unknown. The objective of this study is to analyze the effect of PGV-0 on the Extracellular Signal Regulated Kinase (ERK) phosphorylation in steroido¬genesis…

Expression of receptor advanced glycation end products (RAGE) and histologica…

Diabetes mellitus (DM) is a multisystemic disease characterized by hyperglycemia due to defects in insulin secretion and action, or both. Hyperglycemia is the most important factor in the onset and progress of diabetic complications. Hyperglycemia increases the expression of receptor for advanced glycosylation end products (RAGE) which leads to pancreatic β-cells damage. Yellow soybean (Glycin…

Serum testosterone level and active caspase-3 of Leydig cells of diabetic Spr…

Diabetes mellitus (DM) is known as the main death cau se in the world. This disease cau ses acute and chronic complication. The comm on chronic complication on male reproduction system is the decrease of testosterone level. This hormone is produced in the Leydig cells. Soybeans (Glycin max) has been used in the management of DM to maintain blood glucose level. However, the effect of soybean on …

Curcumin Analogue (Penatagamavunone-0) Induces Lufeal Cell Apoptosis by Incre…

The present study was conducted to investigate the role of curcurnin analogue Pentagamavunone-O (PGV-O) of luteal cell function in apoptosis by examined Bcl-2 and Bax protein expressions. Corpora lutea of rat Sprague-Dawley at 28 days of age after induced by 10 IU pregnant mare's serum gonadotropin (PMSG) were dispersed enzimatically by collagenase. Isolated luteal cells were seeded in 24 well …

Efek Pentagamavunon-0 terhadap Konsentrasi cAMP dan Progesteron pada Kultur S…

Edition

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ISBN/ISSN

0854-1159

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Call Number

Jurnal Kedokteran Yarsi:17(2)93-100