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This research is conducted to analyze the effcet of ethanol extract of daruju root (A. Illiofollus L) on the mice hepatocyte which is inducted by carbon tetrachloride. Ethanol extract of daruju root is fed to the mice (per oral) with 250 mg/kg, 1000 mg/kg, and 4000 mg/kg weight dosage in 7 days. On day 8, the mice sample is given by carbon tetrachloride which is dissolved in olive oil. As negat…
This research is aimed at testing of Tween-80 and DMSO in of Sodium Diciphenac, to increase the penetration of the active ingeredient. The lest of active ingredent was determined by Franz cell diffusion of vertical type by using rat skin and NaCI 0,9% as the recelving solution. The content of penetraining active ingredient was determined by UV-Visible spectrophotometry. The rresults showed the …
Extended-release of soliddispersions of nonsteroidal antiinflammatory drugs ketoprolen were prepared by solvent method using Eudragit RL 100 as the inet caries. The effects of different polymer ratios of Eudragit RL 100 various formulations of solid dispersions on the in vitro release profile of ketoprofen from the powder of solid dispersion system were investigated, The result showed that incr…
Amphetamine-type stimulant (ATS) is a group of substances that have similar properties like amphetamines. The ATS get serious attention, because it stimulates the Central Nervous Sysytem (CNS) as phamacological properties. The ATS in it’s misuse in young generation. This study aims to find out the ATS in urine samples and other content and it’s comperative result of ATS analysis by using r…
The aim of the present study was at preparing and evaluating different formulation of ketokonazole in microemulsion base by using virgine conconate oil (VCO) as oil phase. Tween 80 used sufactant and sorbitol as-sufactant. Five different formulations were formulated with values of oil (5%) and surfactant (35%, 40%, 50%, 55%)and co-surfactant (10%). Mocroemulsion of ketoconazole also made but wi…
Piper betle L is a well known plant used in taditional medicine, espesially used as an antibactteria. The aim ot this research is to compare antibacterial activity and mechanism of inhibition between esential oil etanol 70% extract of betle leaves on some gram (+) becteria. The experimental result showed that MC values for essential oil against Staphylococcus aureus is 7,4% (b/v), Bacillus pumi…
Testosterone undecarnoate was one of the esters of testoterone. Microemulsion was selected as the formula for testoterone undecanote based on the clinical considerations and their physico-chemical properties. This study aims at finding catch optimum conditions for the analysis of testosterone undercanoate in microemulsion by high performance Liquid Chromatography (HPLC) and a vaidation is also …
Sodiumascobyl phosphate is a hydrophilic derivate of asorbic acid, which has chemically more stable. As an antioxidant it can scavengeand destory aggressive oxidizing agents and free radicals that are improtantly involved in the skin aging process. Microemulsion is carrier systems for topical delivery of sodium ascophate. An experiment has been conducted with virgin coconut oil (VCO) as an oil …
Shiitake (Lentinula edodes (Bark) Pegler) is one of the wood mushroom that have a broad benefit. Besides Aiready known as a delicious food, shiiitake fungi can also act as a drug, such as antibacterial, antiviral, anti platelet agggulutination an cholesterol-lowering compound. The research was conducted to test the antibacterial activity of 70% athanol and n-hexane extract from Shitake fungus (…
Cardiac arrest remains a leading cause of death in the world. Although advances in emergency cardiac care has been achieved, the survival rate of those non hospitalized hospital cardiac arrest remains low. Update in guidelines for CPR and emergency cardiovascular, their approach to out of hospital cardiac arrest is far from optimal. This provides an opportunity to advocate cardiocerebral resusc…