Abstract: Synthesis of I ,S-bis(3' -etoxy-4' -hydroxyphenyl)-I ,4-pentadiene-3-on (EHP) by aldol condensation method from ethyl vanilin and acetone, using hydrochloride acid as a catalyst, has been conducted. Identification of the EHP compound was done through interpretation of UV- Vis, FT-IR, GC-MS and NMR data. The antioxidant activity of EHP (ICso 8.66 ug/ml.) is higher than curcumin (ICso 1…
Effects of ratios of ethanol-water as extracting solvent in obtaining extractable material, phenolic 'compounds and antioxidant activity from the herb of Phyllanthus niruri Linn. have been investigated. The ratios tested were 100:0, 80:20, 70:30, 60:40 and 50:50. The results revealed that the ratio of ethanol-water used gave significant effect on extractable material, phenolic compounds and ant…
The production of free radiacals (oxidants) that are not in balance with antioxidant activity can cause cell damage. The need for antioxidant is absolutely necessary not only endogenous but also exogenous. Yellow soybean is one of the plants that have antioxidant activity, which can reduce the effects of free radicals while vitamin E is a powerful antioxidant which is used. This study aims to d…
The stem bark of Garcinia moluensis Lauterb afforded a benzophenone epicambogin (1). The structure was elucidated using IR, MS, NMR spectroscopy and comparison of its spectroscopic data with data reported in the literature. This compound was tested for its bioactivity as antioxidant and toxicity test. The antioxidative activity was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. T…
Chaging from traditional to a modern food consumptionpattern has increased the prevalence of cardiovascular disease in developing countries. Indonesia traditional diet is a good source of antioxident such as spices, fruts and vegetables. This study was conducted to investigate the relation-ship between consumption of spices, fruits and vegetables to cardiovascular disease risks. This was a cros…
Actinobacillus actinomycetemcoitans (Aa) serotype B has been associated with aggressive periodontitis. Gingival epitelial cel is expasitely sensitive to the toxin and may lead to the epithel protective barier disruption. Experimental models show that minocycline is not related to it’s disease. This study, examined antioxidant effects of menocycline to inhibit apoptisis of gingival epithelium…
Vitamin antioxidants administration toward muscle damage on exercise. An experimental study in students of FKP-JPOK Sebelas Maret University. Exercise has dual effects, which not only enhance health and performance but also result in mucular damage. The aim of this study is to determine when the administration of vitamin antioxidants is more effective in reducing the muscular damage. An exper…