Actinobacillus actinomycetemcoitans (Aa) serotype B has been associated with aggressive periodontitis. Gingival epitelial cel is expasitely sensitive to the toxin and may lead to the epithel protective barier disruption. Experimental models show that minocycline is not related to it’s disease. This study, examined antioxidant effects of menocycline to inhibit apoptisis of gingival epithelium…