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Sindroma Erupsi Obat Yang Disertai Eosinofilla Dan Gejala Sistemik (Sindroma Dress)

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Drug rash with eosinophilia and systemic symptoms syndrome (DRESS syndrome) or drughypersensitivity syndrome is an idiosyncratic severe adverse cutaneous drug reaction that begins acutely in the jirst two months (2-6 weeks) after initiation of drug. It's manifestations are fever, rash, absolute eosinophilia, lymphadenopathy, and involvement of internal organ. Pathagenesis of DRESS syndrome is very complex and not well understood Existing theory said that hypersensitivity reaction occurred from abnormal production and detoxification of drug's active metabolites, also by activation and reactivation of Human Herpes Virus 6 (HHV-6). The main management in DRESS syndrome is identifying and withdrawing the causative drugs and administration of long-term systemic steroid therapy.
Key words: DRESS syndrome - severe adverse cutaneous drug reaction - eosinophilia

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

MEDICINUS : Jurnal Kedokteran Universitas Pelita H

Penerbit

Tangerang : FK Universitas Pelita Harapan Tangerang., 2012

Deskripsi Fisik

8p

Bahasa

ISBN/ISSN

1978-3094

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

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Info Detail Spesifik

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Pernyataan Tanggungjawab

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