Urticaria is a circumscribed, erythermatous or white, usually pruritic plaque that changes in size and shape by peripheral extension oe regression during the few hours or days that the individual lesion exist. Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs), resulting in urticaria qnd angioedema, is being observed with increasing frequency. Prevalence rates range from 0.1-0.3%…
Drug rash with eosinophilia and systemic symptoms syndrome (DRESS syndrome) or drughypersensitivity syndrome is an idiosyncratic severe adverse cutaneous drug reaction that begins acutely in the jirst two months (2-6 weeks) after initiation of drug. It's manifestations are fever, rash, absolute eosinophilia, lymphadenopathy, and involvement of internal organ. Pathagenesis of DRESS syndrome is …