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Rasionalisasi Penggunaan Obat Simptomatik dan Obat Lain yang Diberikan Bersamaan dengan Obat Artesunate-Amodiakuin pada Subyek Malaria di Delapan Puskesmas Sentinel Kalimantan dan Sulawesi
Background. Since 2004, Malaria Program in Indonesia has used Artemisinin Combination Therapy (ACT) to replace the chloroquine resistance. The recommended ACT is Artesunate dan Amodiaquine (AAQ) combination for uncomplicated falciparum malaria. To relieve side effects and clinical complaints of malaria , health workers usually gave symptomatic and other drugs in addition to antimalarial drugs. Methods. The methodology implemented in this study was a cross-sectional study to evaluate symptomatic and other drugs given together with antimalarial (AAQ) to uncomplicated malaria subjects (patients) infected by falciparum, vivax and mixed (falciparum dan vivax) plasmodium. Data were collected from case report form in 6 months (July to December 2010) from 8 (eight) sentinels puskesmas (primary health centers) in North Sulawesi, Central Sulawesi, West Kalimantan and East Kalimantan. Results. Total number of cases (89,4%) were given symptomatic and other drugs in addition to antimalarial drugs. Symptomatic and other drugs that mostly given were antipyretic/analgesic (90.8%) and vitamin-mineral (70%). There seemed to be over-use of vitamin-minerals since the indication to giving those medications were not quite clear. Antibiotics were mostly given to subjects with gastrointestinal complaints such as nausea, vomiting, and abdominal pain. The administration of antibiotic for non-bacterial infection were irrational. Antihistamines were given to 94,3% subjects without cold and flu, and this cases also be defined as inappropriate use of medicine. In addition, antacids were also given to 12,5 % subjects without gastrointestinal complaints to anticipate side effects of antimalarial.
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