Badan Penelitian dan Pengembangan Kesehatan sebagai bagian dari Kementerian Kesehatan mendapat amanah sebagai lokomotif pembangunan kesehatan. Produk yang dihasilkan diantaranya merupakan buku ilmiah yang mendukung pelaksanaan kegiatan penelitian kesehatan. Dalam hal ini, ditulis dalam “Bunga Rampai Uji Klinik”. Berbagai penelitian dan pengembangan, serta inovasi teknologi yang terkait deng…
Our previous study of single dose artemisinin-naphthoquine (ANT) in adult majority male patients showed it as a safe, tolerable, and very effective treatment for uncomplicated malaria. More data is required to verify safety and efficacy from other age groups before this new drug could be widely used in Primary Health Care (PHC)s in Indonesia. For this study, we modified the 2009 WHO guidelin…
Active pulmonary Tuberculosis (TB) cases and drug resistance Myco-baterium tuberculosis strain increase the risk of health workers who contact to TB patients. Primary Health Care (PHC) workers in Indonesia have the risk to be exposed to M. tuberculosis in workplace. This study aimed to evaluate the implementation of occupational health and safety concerning prevention of M. tuberculosis tra…
A practical and simple Artemisinin based combination therapy (ACT) with good compliance in adult patients for all malaria species has been shown in the first article: “Efficacy and Safety of Artemisininnaphthoquine versus dihydroartemisinin-piperaquine in adult patients with uncomplicated malaria: a multi-centre study in Indonesia”. It is worth to add data safety and efficacy of …
Indonesia as a malaria endemic country is recommended to use Artemisinin-based Combination Therapy (ACT) for P. vivax malaria. Confirmation of Chloroquine resistant and ACT efficacy for P. vivax need to be investigated for supporting malaria treatment policy. Papua and East Nusa Tenggara (NTT) contribute the main malaria cases in Indonesia. To evaluate efficacy and safety of A…
This study is part of the study with title "Monitoring drug resistance in subjects with P. falciparum and P.vivax malaria in Kalimantan and Sulawesi, Indonesia" which the objective to assess the efficacy and safety of Dihydroartemisinin - Piperaquine (DHP) in patients with malaria vivax in Kalimantan and Sulawesi. The design of study was a cross-sectional study and prospective evaluation of 87 …
Anemia merupakan salah satu dampak infeksi malaria falsiparum dan malaria vivaks. Respon imun ternyata mempengaruhi kadar hemoglobin. Sitokin proinflamasi dan antiinflamasi memainkan peranan penting terjadinya anemia penderita terinfeksi P. falciparum dan P. Vivax.Tujuan penelitian adalah untuk menilai hubungan antara kadar hemoglobin dengan sitokin TNFα, IFNγ, IL12 dan IL10 pada penderita ma…