As the place for taking care of sick people, hospitals nonetheless can play as the source of infections, one of which is nosocomial infection that may lead to many disadvantages. This study was aimed to understand the description of nosocomial infection incidence in Wonosari General Hospital throughout 2011 by conducting an observational study with descriptive approach. The number of samples we…
The continuous use of hard water can cause health disorders as well as economic, aesthetic, and technical problems. According to the regulation issued by the Ministry of Health No. 416/ Menkes/Per/IX/1990 about the quality requirements for clean water, the maximum levels permitted for water hardness parameter is 500 mg/l. Based on the preliminary study conducted at Griya Citra Asri Housing in T…
Background.Alkylation of DNA can occur at various site, however lkylation of the O6-position ofguanine has the strongest mutagenic potential. O6 -Methylguanine is a toxic and mutagenic lesionwhich is formed in cellular DNA by alkylating agents. Alkyl group from carbanium ion can attack DNA forms alkylated DNA especially at O6 position of guanine. O6-ethylguanine mispairs with thymine during r…
Aim: to determine whether serum HER-2/neu level could be used as a prognostic factor in locally advanced breast cancer (LABC) and metastatic breast cancer (MBC). Methods: a prospective cohort study was done in LABC and MBC patients in dr. Sardjito Hospital Yogyakarta from April 2006 to March 2008. Serum concentration of HER-2/neu was measured by ELISA done before and after chemotherapy. HER-…
Otitis media is an inflammation of the middle ear mucoperiosteal without reference to its cause or pathogenesis. The incidence rate in Bandung area was 6.9%. Otitis media caused by Eustachian tube dysfunction might be induced by the use of nasogastric tube (NGT). An observational analytic was conducted to know the effect of NGT on incidence rate of otitis media with effusion in hospitalized pat…
Prevalence of metabolic syndrome (MS) in Indonesia (13,13%) is high andtends to increase. One of the consequences of MS is endothelial dysfunctionleading to cardiovascular disease which is inducted by oxidative stressand inflammation. The aim of the present research is to explore lipid profile,lipid peroxidation, and inflammatory marker level on metabolic syndromewomen in Purwokerto. Thirty wom…
The incidence ofpreeclampsia in Indonesia (1980-2001) was around 6-8% of the total pregnancies with maternal mortality rate 9.8-25%. In preeclampsia, an increase of apoptosis occurs as a result of a decrease ofBc1-2 expression before a pregnancy reached full term. The objectives of this study were to determine placental apoptosis index (AI) in preeclampsia and normal pregnancy, and its correlat…
Background: Histopathological examination is paramount in patients with suspected lung cancer, because it is a gold standard for lung cancer diagnosis. Sputum cytology examination is the only non-invasive examination that can detect lung cancer, besides it is quite cheap and can be used widely. Objective: The aim of this study is to compare whether any sensitivity differences among once 3% sal…
Diet tinggi lemak rantai jenuh ikut berperan sebagai penyebab meningkatnya prevalensi obesitas dan sindroma metabolik A high saturated fatty chains diet play a role in the increasing prevalence of obesity and metabolic syndrome. Profil lipid darah merupakan indikator yang penting untuk mengetahui faktor resiko kelainan kardiovaskuler. Penelitian ini bertujuan untuk mengetahui pengaruh diet ting…