Background.Alkylation of DNA can occur at various site, however lkylation of the O6-position ofguanine has the strongest mutagenic potential. O6 -Methylguanine is a toxic and mutagenic lesionwhich is formed in cellular DNA by alkylating agents. Alkyl group from carbanium ion can attack DNA forms alkylated DNA especially at O6 position of guanine. O6-ethylguanine mispairs with thymine during r…
Prevalence of metabolic syndrome (MS) in Indonesia (13,13%) is high andtends to increase. One of the consequences of MS is endothelial dysfunctionleading to cardiovascular disease which is inducted by oxidative stressand inflammation. The aim of the present research is to explore lipid profile,lipid peroxidation, and inflammatory marker level on metabolic syndromewomen in Purwokerto. Thirty wom…