Sasaran Aksi Pentagamavunon-O pada Steroidogenesis Sc! Luteal Melalui Penguku…

Introduction: Pentagamayunon-0 (PG V-0) compound, a curcurnin analog, can inhibit steroido¬genesis of luteal cell culture by inhibiting the production ofprogesterone. The action site of PG V¬0 on steroidogenesis of luteal cells is still unknown. The objective of this study is to analyze the effect of PGV-0 on the Extracellular Signal Regulated Kinase (ERK) phosphorylation in steroido¬genesis…

Selaginella active fractions induce apoptosis on T47D breast cancer cell

Apoptosis is an important target on anticancer mechanism. The purpose of this research is to investigate apoptosis induction of Selaginella plana Hieron active fractions on T47D cells. Absolute ethanol was used to extract Selaginella /Diana powders. Ethanolic extract was dilluted by methanol:water (4:1) and then fractionated by hexane (S Hex), methylene chloride (S_MTC), ethyl acetate (S_EA), a…

Pengaruh Perlakuan PGV-1, PGV-0 dan Kurkumin terhadap Protein yang Terlibat d…

Previous experiments show ed that curcumin analogue (PGV-1) inhibited breast cancer cell (T47D) growth at G2-M phase and induced cell apoptosis. This experiment was conducted to investigate the molecular effect of another curcumin analogue, PGV-0 and curcumin on the cell cycle progression and apoptosis as compared to the PGV-I. Flowcytometric method was conducted to analyze the effect of PGV- 1…

Pengaruh Perlakuan PGV-1, PGV-0 dan Kurkumin terhadap Protein yang Terlibat d…

Previous experiments showed that curcumin analogue (PGV-1) inhibited breast cancer cell (T47D) growth at G2-M phase and induced cell apoptosis. This experiment was conducted to investigate the molecular effect of another curcumin analogue, PGV-0 and curcumin on the cell cycle progression and apoptosis as compared to the PGV-1. Flowcytometric method was conducted to analyze the effect of PGV- 1…

Peningkatan Efek Sitotoksik Doxorubicin Oleh Naringenin pada Sel Kanker Payud…

Abstract: Doxorubicin is one of the standard regiment for breast cancer chemotherapy, but resistance to this agent is often occured and long period usage will induce cardiotoxicity. Therefore, combination therapy (eo-chemotherapy) is needed to improve the efficacy of doxorubicin and to reduce its systemic toxicity. Naringenin is one of the most abundant flavonoids in citrus fruits which showed …

Efek Pentagamavunon-0 terhadap Konsentrasi cAMP dan Progesteron pada Kultur S…

Edition

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ISBN/ISSN

0854-1159

Collation

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Series Title

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Call Number

Jurnal Kedokteran Yarsi:17(2)93-100