Enhanced oxidative stress and changes in antioxidant capacity are considered to play an important role in the pathogenesis of chronic diabetes mellitus. Wistar male rat (n=40) were allocated into three groups, control group (n=10) and quercetin (QR) group that received 15mg/kg (IP) QR, (n=10), and Diabetic group that received 55mg/kg (IP) streptozotocin (STZ) (n=20) which was subdivided to two …
Diabetes mellitus (DM) is a multisystemic disease characterized by hyperglycemia due to defects in insulin secretion and action, or both. Hyperglycemia is the most important factor in the onset and progress of diabetic complications. Hyperglycemia increases the expression of receptor for advanced glycosylation end products (RAGE) which leads to pancreatic β-cells damage. Yellow soybean (Glycin…
A formulation containing 40% of honey, 30% of black cumin, 20% of propolis and 10% of royal jelly has been available in the market for the treatment of diabetes. Although each content of the formulation is proven to possess antioxidant and antihyperglycemic activities, its combination effect has not been evaluated yet. The aim of this study was to evaluate the effect of this formulation on bloo…