Ovalbumin is known as mast cell deranulatin agent through the FC€/RI aggregation. Carboxymethyl chitosan (CMC5), a biocompatible cationic polymer was evaluated to reduces mast cell degranulation induced by ovalbumin. In this experiment, Wistar rats were devided into 5 groups which consist of 1 control group and 4 allergen groups> Among the allergen group, 3 group were trated with carboxymethy…
PGV-1 or 2,5-bis(4’-hydroxy-3,5’-dimethylbenzylidene) cyclopentanone and RGV-2 or 2,5-bis(4’-hydroxy-3’-5’-diethybenzylidene)cyclopentanone are tro benzylidene cyclopentanone analogues of curcumin. In or study, we ivestiggeted the effects of these compounds on the β-hexoaminidase enzyme relese from mast cell culture (RBL-2H3 cell line,). Thapsigargin and lonomycin were used as intrac…