Background: This research is aimed to prove the role of Mahkota Dewa polyphenol in the up-regulation Bax and down-regulation in strain Balblc mice which inducted with benzo(a)pyrene (BaP). Method: Post test control group design with 30 strain Balblc mice sample, aged 1-2 weeks, weighed 20-30 grams, healthy mice condition. All mice inducted with BaP and then randomized into 2 groups, which wer…
Peripherallung tumor is defined in most studies as tumorthat are not visible beyond the visual segmental bronchi and located >2 cm in all directions around the proximal bronchial tree. Localised peripheral pulmonary tumor is commonly encountered in clinical practice and frequently require tissue diagnosis to project a treatment plan. The investigation of a peripheral lung tumor is a challenging…
Background: The Ki-67 protein is a biomarker associated with cell proliferation and from some literature it can be valuable negative prognostic factor in non-small cell lung cancer. We investigated the Ki-67 protein expression in resected non-small cell lung cancer to evaluated the impact on clinicopathological characteristics and postoperative prognosis. Material and Method: Using monoclonal …
Background: Histopathological examination is paramount in patients with suspected lung cancer, because it is a gold standard for lung cancer diagnosis. Sputum cytology examination is the only non-invasive examination that can detect lung cancer, besides it is quite cheap and can be used widely. Objective: The aim of this study is to compare whether any sensitivity differences among once 3% sal…
Methods: We performed a cross sectional, retrospective study in Persahabatan Hospital. We used medical Introduction: Malignant pleural effusions (MPE) are caused most commonly by carcinomas of the breast, lung, gastrointestinal tract or ovary and by lymphomas. In male patients about half of malignant effusions are caused by lung cancer. With lung cancer, a malignant pleural effusion may be the …
Introduction. The tumor supressor gen p53 mutation encodes a protein that inhibits programmed cell death (apoptosis). The protein is expressed in basal cells in normal human epithelium, but no data are available on the frequency or clinical importance of its expression in carcinoma. We studied p53 mutation protein expression in post surgery tissues of patients with non-small cell lung carcinoma…
Response rate of regiment carboplatin plus etoposide for non-small cell lung cancer is inferior than regiment used new agent as paclitaxel, docetaxel or gemcitabine. On the other hand, the combination response of chemoradiotherapy could efficacy for non-small cell lunf cancer However, there is still controvers about the toxixities if full dosed chemotheapy is used in concurrent chemoradiotherap…