Background: This research is aimed to prove the role of Mahkota Dewa polyphenol in the up-regulation Bax and down-regulation in strain Balblc mice which inducted with benzo(a)pyrene (BaP). Method: Post test control group design with 30 strain Balblc mice sample, aged 1-2 weeks, weighed 20-30 grams, healthy mice condition. All mice inducted with BaP and then randomized into 2 groups, which wer…