Carbamazepine (CBZ) is an anticonvulsant widely used for epilepsy treatment.. However, it is difficult to establish suitable dosage regimens for this drug because of the variation on its pharmacokinetics profiles. A lot of evidences indicate that ethnic differences may affect pharmacokinetics and hence dosage requirements. The study was conducted to document pharmacokinetic profile of CBZ and i…
Shelf-life determination of extemporaneous carbamazepine capsule 100 mg dosage form had been studied by dissolution test. The carbamazepine capsules were storage approximately three weeks in ambeient temperature and 72 percent humidity. The dissolution test of each sample was assayed by UV spectrophotometry at maximum λ equals 224 nm. The result showed that the shelf life of extemporaneous car…