The present study was conducted to investigate the role of curcurnin analogue Pentagamavunone-O (PGV-O) of luteal cell function in apoptosis by examined Bcl-2 and Bax protein expressions. Corpora lutea of rat Sprague-Dawley at 28 days of age after induced by 10 IU pregnant mare's serum gonadotropin (PMSG) were dispersed enzimatically by collagenase. Isolated luteal cells were seeded in 24 well …