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Econazole is an azole antifungal agent which can block the calcium release-activated calcium (CRAC) current in human leukaemic T cell line. The phenomenon is also possible to occur in mast cell such as RBL-2H3 (rat basophilic leukemia) cells, a tumor analog of mast into the cells, a tumor analog of mast cells. In the study, we investigated effect of econazole on 45 Ca 2+ uptake into the cells…
Tuberculosis (TB) is still a problem in community health with high rate of mortality. The case became much more complicated due to emerge of Mycobacterium tuberculosis which are reistant to the drugs. This caused the movement of attention from the first line drugs to fluora-quinolon (FQ) as alternative drug. The aim of this research was to do analysis the mutation which causing the resistance o…
Long term goal of this study is the use of combrang (Nicolaia speciosa Horan) as an ingredient of traditional medicine after after being evaluated through predicinal testing and clinical trials both extract and its bioactive compounds. This study includes analgesic-antiinflammatory activity test of n-hexane, chloroform, ethyl acetate and methanol extract of combrang stem. Analgesic test againt…
Ranitidine HCI is an H-2 receptor antagonista for the treatment of peptic gastric secretion with small biovailability, so that should be developed in a sustained release dosage form are retained in the stomach. Ranitidine HCl floating tablet was formulation by effervescent system. Simplex lattice design was applied to optimize the formula of ranitidine HCl floating tablet by varying levels of …
The characteristic of emollient cream that contained of avocado butter as anti-aging is influenced by amount of avocado butter used. The research has a purpose to exploit and develop usage of avocado butter in the flield of cosmetic. The researh has done by making A/M cream used 1-11% avocado butter with melting and mixing method at temperature of 70-75⁰C. Stability of product creams were be …
Mucoadhesive tablet for asthma treatment were prepared by mixing theophylline with two variations of polymers. The purpose of this research was to controlled drug rellease from the dosage form. Theophylline mucoadhesive tablets were prpared by direct compression using chitosan and sodium carboxymethy lcellulose as mucoadhesive polymers. Mucoadhesive strength measured using rabbit gastric mucosa…
Niosomes are vesicles system that have applications in the delivery of lipophilic, hydrophilic and amphiphilic drugs. Ketoprofen, is very insoluble in water and cause gastric irritation when taken orally. It is very important to water and cause gastric irritation when taken orally. It is very important to develop a transdermal delivery system for ketoprofen. This research was aimed to design ni…
Effect of water extract of black seed on uric acid metabolism in hyperuricemia mice models were studied. The influence of water extract of black hyperuricemia mice models were studied. The influence of water extract of black sed on uric acid biosynthesis was examined using mice treated by 250 mg/body weight potassium oxonate intra peritoneal. The result showed that water extract of black seed (…
Abstract: The general objective this research was to study effects of the mperature and time of heating on the stability and the organoleptic qualitiy of Micronutrients Fortified Biskuit strobery sandwich . Research was an experiment with completely randomized factorial design. The results showed that the temperature and duration of heating indicated no significant effects on the stability of…
This Research to determine the effect of giving dietary rice bran (bekatul) against cholesterol, triglycerides, LDL, HDL, SOP dan MDA in the white rat (Rattus norvegicus L). This research is true experimental research. Using a completely randomized design method using a test with one way annova. Variabel in this study is the bran (bekatul) (Idependent variables) and levels of cholesterol, trigl…