PGV-1 or 2,5-bis(4’-hydroxy-3,5’-dimethylbenzylidene) cyclopentanone and RGV-2 or 2,5-bis(4’-hydroxy-3’-5’-diethybenzylidene)cyclopentanone are tro benzylidene cyclopentanone analogues of curcumin. In or study, we ivestiggeted the effects of these compounds on the β-hexoaminidase enzyme relese from mast cell culture (RBL-2H3 cell line,). Thapsigargin and lonomycin were used as intrac…
Alpha tocopherol, also has a non anti-oxidant activity that corrrelates with inhibition of PKC-alpha isozyme activity. Several studies confirmed its role in ihhibition of vascular smooth umscle proliferation. Inhibition of stromal cell proliferation is an alternative method of prevention of BPH. The aim of this in vitro study is to confirm that alphatocopherol, by its ability to inhibit PKC-alp…
To prove that glucose treatment in human prostatic stromal cells (GPSC) culture wound increase PKC alpha isozyme activity. Primary cuktures of HPSC were obtained from patients with blader outlet obstruction caused by benign prostatic enlargement. The effects various contrations of glucose (5,10.15.20.30.35 micro-Mol) on PKC-alpha isozyme activity were examined quantitatively by spectropotometry…
To prevent lyses of the blood cells that consist of erythrocyte and leukocyte in urine. It is necessary to preserve it by storing it at 4ºC or giving 37% formalin. Therefore, one group post design experimental study was conducted to confirm the influence of preservation toward the number of blood cells in urine. The objective of this study was to verify the influence of 3-hour storage at room …
In developed countries, cancer represents the second death cause after cardiovascular disease. In Indonesia, cervix cancer represents the most cancer case at wonan. Continous efforts to find the effective cancer drug with the small sede effects were still conducted. One of the way for obtaining that purpose is by exploring the source of nature cytotoxic activity of Ageratum conyzoides L, leaves…
Mas cell are derived from haematopoletic progenitors in the bonemarrow. Developing mast cell subsequently migrate to peripheral tissues, such as the skin, mucosa and air way, There they terminate their differentiation under the influence of factors in the tissue micro-environment. This study aimed to know istribution and structure of mast cell on rat mesentery. The masentary was stained with a…
Background: Adolescent brain may be more susceptible to damage by ethanol administration may cause morphological changes in the hippocampus, followed by deficit in the hippocampal function, including the impairment of memory. Objective: The aim of this study were to investigate the changes in the total number of pyramidal cells in CA1 and CA3 of hippocampus, and the relationship between these c…