Zingiber officinate, Rosc, is a well known plat which can be used for the treatment of various diseases, and has been reported as an effective medicinal plant against Dirofilaria immitis in animal. The volatile oil and the pungent of Zingiber officinate, Rosc. have been effectively used larvae stage 3 (L3) B. malayi in vitro study. This study was designed to investigate the effect of the volati…
In another experiment, we have demonstrated that garlic protected rat liver against CCl4 intoxication, indicated by low levels of plasma GPT activity of rats receiving garlic extract and CCl4. As leek is a member of Allium genus, it could posses the same action as garlic. A group of nine rats were treated with 0.275 mg CCl4/g body weight in a single dose and the plasma GPT activities were deter…
The ability of leek to prevent liver damage in rats intoxicated with CCl4 has been demonstrated histopathologically as well as based on enzymatic findings by observing GPT levels in serum. This study was performed to gain an understanding, at least partially, of the hepatoprotective mechanism of leek. A number of rats were divided radomly into three groups of seven animals. The first group, wit…
Malaria is a common disease caused by infection of Plasmodium spp. Based on retrievals is library reference it has been discovered that a number of chemical compounds, isolated from fruit-bearing plants, contain anti-protozoic active substances. These compounds are, among others, found in chemical structures of alkaloide, terpene, quinone, and phenolic. Research on traditional medicinal plants …
A toxicity test was performed on separately 11 extracts of Indonesian medicinal plant (Elaeocarpus gramiflorus J.E. Smith, Vitex negundo L., Leucaena leucocephala (Lmk) de Witt, Borreria articularis (L.f) F.N. Will, Ardissia humilis vahl., Achyranthus bidentata L., Hyptis capitata Jack., Gynura procumbens (Lour.) Merr., Annona squamosa L., Annona murricata L. and Artemisia vulgaris L.,) by 'Bri…
Malaria is still a major public health problem in Indonesia, and prevalence rate is high in some areas. To control malaria is extremely difficult due to interaction between host-agent and vector. Malaria falciparum parasites have been resistant to chloroquine due to the long and improver use. The alternative drugs such as fansidar and quinine are more toxic and often produce a severe side effec…
Malaria is a common disease caused by infection of Plasmodium spp. Based on retrievals in library reference it has been discovered that a number of chemical compounds, isolated from fruit-bearing plants, contain anti-protozoic active substances. These compounds are, among others, found in chemical structures of alkaloide, terpene, quinone, and phenolic. Research on traditional medicinal plants …
Determination and characterization of Gynura procumbens (Lour) Merr asparaginase has been studied and evaluated. Determination of asparaginase activities were carried out by Bergmeyer's method and the protein in solution was assayed by Lowry's method with bovin serum albumin as protein standard. The result of this observation as follows : the spesific activities of Gynura procumbens asparaginas…
Finding new substances from natural resources is quite important, especially those possessing medical usage. This experiment was perfomed in order to isolate and elucidate the stucture of pentacyclic triterpene and sterol substances from Eupatorium in lifolium H.B.K. leaves. The structural elucidation of those substances was performed using IR, UV, mass spectrometer 1H and 13C NMR. The result s…
Background: Piper retrofactum Vahl has been used as traditional medicine for a long time. Objective: to compare: (1) piperine alkaloid and other alkaloid of cabe Jawa from Madura and Lamongan, by Thin Layer Chromatography (TLC) method,(2) the effective dose (ED50) of anticonvulsive of infusum extract and mefenemic acid by shock seizure (MES) and metrazole seizure (MET) in Mice, (3) ED50 of anal…