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Background:Schistosomiasis is still a health problem in Central Sulawesi. Snail Oncomelania hupensis lindoensis, the intermediary for schistosomiasis is widespread in this region. Eradication has been done by spraying chemical molluscicides. This study aimed to identify the class of chemical compounds in the methanol extract of red castor seed. Methods: The study was conducted in May 2009. R…
Latar belakang, kombinasi buah sirih (Piper betle L), daun miyana (Plectranthus scutellarioides (L.) R. BR, madu dan kuning telur dimanfaatkan oleh masyarakat Sulawesi Utara untuk mengobati malaria. Diharapkan kombinasi buah sirih (Piper betle L), daun miyana (Plectranthus scutellarioides (L.) R. BR, madu dan kuning telur juga memiliki potensi untuk merangsang respon imun. Penelitian ini dilak…
Sikatrik kornea dapat menimbulkan gangguan penglihatan mulai dari kabur sampai dengan kebutaan. Sikatrik kornea dapat bentuk ringan (nebula), sedang (makula) dan berat (leukoma). Gangguan kornea merupakan penyebab kebutaan kedua didunia setelah katarak. Sikatrik kornea lebih sering disebabkan oleh infeksi, xeropthalmia dan trauma. Belum ada data yang akurat mengenai prevalensi sikatrik kornea d…
Siwak (Salvadora persica L.) adalah sejenis tumbuhan yang (terdapat dalam Al-Qur’an, Surah 34:16) ranting dan akarnya digunakan sebagai sikat gigi. Pada penelitian ini telah dilakukan uji imunomodulator dari ekstrak air dan alkohol ranting siwak dengan melihat peningkatan aktivitas/spesific phogositosis activity (SPA) dan Kapasitas/index phagositosis (IP) sel makrofag peritonium mencit (Mus m…
Filariasis merupakan penyakit menular menahun yang disebabkan oleh cacing filaria dan masih menjadi masalah kesehatan di Indonesis khususnya di daerah yang masih tertinggal. Kabupaten Sumba Tengah Propinsi Nusa Tenggara Timur merupakan daerah dengan kasus klinis cukup tinggi. Tahun 2007 jumlah kasus klinis filariasis di kabupaten Sumba Tengah sebanyak 360 kasus. Tujuan survei ini adalah untu…
Apoptosis is an important target on anticancer mechanism. The purpose of this research is to investigate apoptosis induction of Selaginella plana Hieron active fractions on T47D cells. Absolute ethanol was used to extract Selaginella /Diana powders. Ethanolic extract was dilluted by methanol:water (4:1) and then fractionated by hexane (S Hex), methylene chloride (S_MTC), ethyl acetate (S_EA), a…
Non Steroid Anti-Inflammatory (NSAID) is one type of Anti-Inflammatory drug that is used to treat pain in patients of osteoarthritis (OA) and rheumatoid arthritis (RA). The use of NSAIDs can cause gastrointestinal side effects. To prevent the side effects, NSAIDs are prescribed in combination with gastroprotective agent (GPA). The aim of the study is to determine the factors considered in the G…
Psidium guajava L. (Myrtaceae) is a well known plant in Malaysia and Indonesia. Its leaves extract was found to possess antidiarrhea, antimicrobial, hepatoprotective and antioxidant activities. Objective of this research is to isolate an antioxidant subtance from Red Psidium guajava L. leaves. The crude leaves was extracted using Soxhlet apparatus by gradual polarity of three different solvents…
Using of curcumin as anti cancer agent is restricted by its low solubility, therefore it has low bioavability. This obstacle can be solved by the development of curcumin nanoparticle. Nanoparticle technology has been started to be developed as an alternative solution to improve drug delivery pofile, especially for the less bio-available chemical. This study was aimed to develope nanocurcumin fo…
HEPATOPROTECTIVE EFFECT OF GAMAVUTON-0 AGAINST D-GALACTOSAMINE/LIPOPOLYSACCHARIDE-INDUCED FULMINANT HEPATIC FAILURE