Twenty eight newborn mice (Mus musculus) consist of 14 males and 14 females have been treated with benzo(a) pyrene (BP) which were dissolved in dimethylsulfoxide (DMSO) solution. The lung tumour induction has been done by intraperitoneally injection of the solution at the first day of age using doses of 0.2 umol BO/0.025 cc DMSO, 8th day of age using doses of 0.4 umol BP/0.025 cc DMSO, and 15th…
The incidence of lung malignancies gradually increase. Mostly lung cancers detected in a late stage as a result of extensive spreading locally and or distant metastases. It will be easy to detect when lesions reach a sufficient size to ulcerate into a bronchus. Cytology sputum could give high acuracy diagnoses, in early stage so the aim of this study was to determine the effectivity of cytology…