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To know the clinical picture of subjects with NASH in Jakarta, Indonesia and the prevalence of insulin resistance. TNF-α, and adiponectin levels among them. This was a comparative cross-sectional study between patients with histopathologically confirmed NASH and normal subjects. The population of study was patients with fatty liver without history or significant consumption of ethanol. Patient…
To recognize the correlation between lower-extremity functional status and obesity in patients with type-2 DM with PAD complication (with and without peripheral arterial disease). The study was a cross-sectional study conducted at Outpatients Clinic of Internal Medicine, Dr. Sardjito Central General Hospital in August-December 2006. Fifty-five subjects who were patients with type-2 DM aged more…
Dyspepsia is syndrome characterized by symptoms and signs o upper gastrointestinal tract and the adjacent organs. It is estimated that 25% of the community have symptoms of dyspepsia syndrome. One-third of patients who visit general physician practices are patients with dyspepsia syndrome; and half of patients who visit gastroenterologists are also patients with dyspepsia syndrome. Dyspepsia sy…
Human immunodeficiency virus type I (HIV-1) has long been a major problem to handle. Its existence is incurable (yet) and has reached pandemic proportions despite strictly-controlled epidemiological surveillance. The current treatment regimen involves the use of multiple antiretroviral agents (known as HAART) is very complex and may harm patients through its serious risk of toxicities. Moreove…
Beta cell dysfunction in type-2 diabetes mellitus holds an important role not its pathogenesis, but also on the progression of the disease. Until now, diabetes treatment cannot restore the reduced function of pancreatic ß cell. Mc Intyre et al stated that there is a factor from the intestine which stimulates insulin secretion as a response on glucose. This factor is known as incretin. It is a…
To assess clinical factors associated with partial hip replacement surgery failure and to develop a scoring system to predict it before treatment. This was a historical cohort studyof hip fracture cases underwent partial hip replacement in Siaga Raya Hospital, Jakarta between Januari 1997 and December 2006. Patients clinical assessment included sex, age at surgery, ambulatory state number of un…
Thrombotic complications in acute leukemia are often underestimated because bleeding complications generally dominate the clinical picture. While there are many thrombogenic factors shared by both solid tumors and leukemia, many additional prothrombotic feactures are present in leukemia. The prothrombotic factors include hyperleukocytosis, increased expression of tissue factor and its activatio…
To evaluate BDM and bone resorption marker in HIV-infected patients in Cipto Mangunkusumo Hospital, Jakarta. A cross-sectional study was performed between February and May 2008 in adult HIV-infected patients who had not been treated with antiretrovirals. BMD was measured at the lumbar spine by dual energy X-ray obsorptiometry (DEXA) bone densitometer (Lumar Prodigy, GE Medical System, USA), Whe…
To obtain the prevalence of dyslipidemia and other cardiovascular risk factors in subjects with undiagnosed DM in Jakarta Indonesia. Data were obtained from surveillance of primary non-communicable disease in five regions in Jakarta, Indonesia, conducted in 2006. Targeting for 1,800 samples, we performed a purposive and simple random sampling of subjects within the age range of 25-64 years old …
To recognize the prevalence of impaired fasting glucose level (IFG) and impaired glucose tolerance (IGT) in general population of Depok Area. West Java . The study was conducted in a population with age ≥ 25 years., in Depok Area, West Java, which was selected by using two stage random sampling. Data were collected by using the Step Wise Approach of WHO. Subjects without previous diabetes his…