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In the last few years there are tendency for cancer study to develop in discovery of new chemical entity (NCE) for new drugs. The needed of NCE based on reality that cancer can be used at one therapy and be implemented as a solution to inhibit a resistant level and very useful in recovery time. Natural products are the most important sources of INCE and could be used from plants. Animals or min…
The study is a systematic empirical analysis to test some hypotheses. The objectives were (1) to analyze the sufficiency of government subsidy for poor people to cover the cost of hospital care for the hospital to reach cost recovery, and (2) to test whether economic theories can be used to analyze factors effecting the sales volume of product/service of public general hospital. Population stud…
Acute diffuse otitis externa (ADOE) is one the common diseases in ENT Department, Dr. Sardjito Hospital, with the frequency of 9-12%. The most common microorganism found is Pseudomonas aeruginosa. Infection usually occurs after taking a bath, washing hair, and scratching the external ear canal. Treatment of acute diffuse otitis externa which consists to topical preparations, i.e. antibiotics a…
One of the factors that determine the success effficien wound healing is wound healing is wound healing rate, that can be achieved by increasing cell proliferation, angiogenesis or neovascularisation, and extracellular production . Dermal fibroblast is cell that plays an important role in wound healing. Fibroblast proliferation and neovascularisation are critical elements in granular tissue for…
Almost 16% from all of the total births in the developing countries are low birthweight babies. Low birthweight babies are an important contribution in neonatal mortality and morbidity worldwide, and contribute to almost 70% f the total neonatal deaths. Proportion of the low birthweight babies in the developing countries is 90% of the total low birthweight babies around the world, which is 20 m…
Dengue virus infection is an acute febrile diseased by 4 sero-type viruses. The transmission via mosquito vector Ae. Aegypti. The morbidity of dengue virus infection is quite high and the mortality below 5%. The most dangerous form is dengue shock syndrome, the mortality is very high. The effort to reduce morbidity and mortality is improvement of the clinical management and control of vector. T…
About 30% patients with chronic idiopathic urticaria (CIU) have circulating histamine-releasing autoantibodies against the α-subunit of high affinity IgL receptor (Fc€RIα), or IgE. This suggroup of patients has a disorder commonly referred as autoimmune urticaria. This study was conducted to reveral the autoimmune urticaria cases in Indonesia patients. The autologous serum skin test (ASST) …
UVB radiation may act as immunosuppressive agent through angerhans cels (LCS) depletion correlated with cyclobuthane pyrimidine dimer (CPD), as the most mutagenic photoproducts. Other studies showed that olive oil can prevent various human cancers which are defect of immune-surveillance. The effect of olive in the UVB-induced LCs depletion is still unclear. To discover the topical effect of ext…
Wrinkles is caused by a decreased by a decrease in collagen synthesis an incease in collagen degradation. Collagen synthesis depends on fibroblast proliferation. Collagen synthesis needs glucose, so that collagen synthesis may be expressed by the increase in glucose uptake. Skin rejuvenation with heating may increase the collagen synthesis. The effect of short-term heating and optimal temperatu…