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Nilai Batas dan Indikator Obesitas terhadap Terjadinya Diabetes Mellitus Tipe 2
Obesity is a risk factor of type 2 diabetes mellitus (T2DM), but the obesity indicator having most clear association still varies. The purpose of the study was to determine cut-off point of three different indicators of obesity body mass index (BMI), waist circumference (WC) and waist-height ratio (WHtR) and compare the three indicators of obesity in detecting of T2DM.
The study was a secondary data analysis using data of baseline cohort study of non communicable desease. Total sample for the analysis was 1415 adult subjects. Multiple logistic regression and Receiving Operating Characteristic (ROC) methods implied to analyze the assosiation.
The results showed that cut - off point and strength of the relationship using BMI was more than 26 kg/m2 (Se 0.65, Sp 0.64; Area Under the Curve (AUC) 0.67 ), OR 2.45 ( 95% CI 1.66 - 3.62 ), WC men and women was more than 81 cm ( Se 0.63; Sp 0.63; AUC 0.68), OR 2.43 ( 95% CI 1.65 - 3.57), and WHtR was more than 0.53 ( Se 0.70; Sp 0.60; AUC 0.69) OR 2.68 ( 95% CI 1.79 - 4.01). The conclusion of this study is that the strength of assosiation among the three indicators of obesity and the type 2 diabetes is similar after controlled by age, family history, hypertension and physical activity.
Keywords : type 2 diabetes mellitus, receiving operating characteristic, indicators of obesity, area under the curve
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