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Studi Monitoring Efek Samping Obat Antituberkulosis FDC Kategori 1 di Provinsi Banten dan Provinsi Jawa Barat
The result of Basic Health Research in 2007 shown that lung tuberculosis cases spread out all over Indonesia. Meanwhile, the 2010 Basic Health Research shown the prevalence of lung TB was 725 per 100,000 populations. Side effects are among the causes of therapy drop out thus resulted in bacterial resistance which further caused the severity of TB.
This research aimed to explore the information of side effects experiences caused by TB drugs therapy as well as to monitor adherence. The research was a time series research, conducted to new patients diagnosed as having lung TB in 10 public health centers (PHCs) in Banten and West Java provinces on May 2011. Those patients were followed up to 6 months until the research was terminated. Patients’ experiences of side effects were collected by monthly interview, when they came to the PHCs to take drugs or during patient’s home visit by the PHC staff. Monitoring of adherence was conducted by counting the tablet at patients’ home. The sample was 92 patients, whom all were counted as adhering the therapy. The most frequent side effect in the first and fifth months was nausea; in the second month was dizziness; and in the third, fourth and sixth month was neuromyalgia. Other side effects reported were drowsiness and weakness in the first three months. Based on the result, it is concluded that by health provider monitoring, the side effects can be identified and had not caused low adherence. This can be the result of good communication between patients and health provider about TB therapy. It is recommended that side effects and adherence monitoring should be conducted by emphasizing on patients and provider communication. In addition, laboratory monitoring should be conducted
periodically.
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