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Perbandingan Penggunaan Diazepam Rektal Dan Midazolam Intravena Sebagai Sedasi Untuk Prosedur Ct Scan Kepala Penderita Pediatri Di Rsu Dr. Soetomo Surabaya (Comparison of Rectal Diazepam And Intravenous Midazolam As Seda Hon For Pediatric Patients Undergoing Head Computed Tomography At Dr. Soetomo General Hospital Surabaya)

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Background and Objective: Invasive diagnostic, radiology and minor surgical procedures on pediatric patients outside the operating room setting have increased in the last 5 years, such as Computed tomography scanning have been known as noninvasive neuroradiology technique since 1973. Childrens who undergo computed tomography (CT) often require sedation due to uncooperativeness to minimize motion artifacts. Currently, benzodiazepines are popular preanesthetic medications because their anxiolytic, sedative, and amnestic properties are combined with minimal cardiovascular and respiratory depression. Midazolam are frequently used for sedation because of amnestic effect, easy to use and short acting. Diazepam could be used for sedation to pediatric patients because of easy to use, easy to obtain, cheap and available in suppositoria, that could be used if we cannot find the intravenous line.
Subject and Method: 30 patients are devided randomly into 2 groups, one group are given intravenous midazolam 0.05-0.1 mg/kg, and other group are given rectal diazepam 5 mg. Before the sedation, the parents of the patients were explained the sedation techniques, vital signs observation during the sedation until in the recovery room.
Results: The sedation level are increase in two groups (p>0.05). There are vital signs changes in two group but not significant. No side effects such as bradycardia, hypotension, bradypneu, desaturation dan nausea-vomiting are occured. Recovery time between two groups are different but it is not significant (p=0.851).
Conclusion: Rectal diazepam 5 mg has sedation effect as the same as intravenous midazolam 0.05-0.1 mg/kg.
Keywords : Diazepam, midazolam, sedation, pediatric, neurodiagnostic, CT scan.

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Jurnal Neuroanastesia Indonesia, 02 (01) 2013 : 10

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Bandung : Indonesian Society of Neuroanesthesia & Critical Care INA_SNACC., 2013

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12p

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2088-9670

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