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HE4 has a High Diagnostic Value to Detect Epithelial Ovarian Cancer (HE4 Memiliki Nilai Diagnostik yang Tinggi untuk Mendeteksi Keganasan Ovarium Tipe Epitel)

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Objective: To find out the diagnostic value of CA125 and HE4 as a tumor marker, and also RM1 and ROMA as a malignancy predictor in patients with ovarian tumors.

Methods: This study was a diagnostic study using cross-sectional design.This study was performed in Jakarta from November 2010 to May 2011. One hundred and twenty eight serum samples of patients diagnosed with ovarian tumors were collected before undergoing surgery in Dr. Cipto Mangunkusumo General Hospital. The CA125 and HE4 levels were then examined. The histopathological examina¬tion of tissue specimens were performed in Department of Pathol¬ogy Anatomy in RSCM. For statistical analysis, we used a 2x2 table to produce ROC-AUC curve.

Results: The median value of HE4 and CA125 serum concentrations was higher and more significant on patients with ovarian malig¬nancy than patients with benign ovarian tumor (p

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Indonesian Journal of Obstetrict and Gynecology, 1

Publisher

Jakarta : Indonesian Society of Obstetetrict and Gynecology., 2013

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5p

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2338-6401

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