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Genotype and Transmission Human Immunodeficiency Virus-1 in Seven Provinces in Indonesia
Background:Previous studies in Indonesia with a limited sample of HIV-1 subtypes revealed that HIV-1 subtype distribution and mode of transmission differed between the regions. This analysis aimed to describe subtypes and mode of transmission of HIV-1 in wider area in Indonesia.
Methods:This analysis used a part of HIV/AIDS cross sectional study in seven provinces in Indonesia in 2011 among HIV/AIDS purposive selected cases visited Volunteer Care and Treatment (VCT) clinics in seven provinces (North Sumatera, West Sumatera, Riau islands, South Sulawesi, North Sulawesi, Maluku, and Papua). For each province was selected 1 or 2 hospitals purposive.
Results: AE subtype of HIV-1 was existed in all participating. Subtype B was found in almost all provinces except in Riau islands. The other type (A, C, and AG) found in 2 provinces only, and the rarest type (D) found in one province only.
The high proportion of transmission was through heterosexual in all provinces except in South Sulawesi. The percentage of the common transmission by intra venous drug user (IDU) IDU occurred in South Sulawesi, whereas via perinatal transmission occurred in Papua.
Conclusion: HIV-1 subtype distribution and mode of transmission differed between the provinces. The AE subtype HIV-1 was existed in all provinces, whereas among provinces the highest proportion transmission via perinatal occurred in Papua. (Health Science Indones 2012;2:xx-xx)
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