Text

Pemacuan Apoptosis oleh Fraksi Kloroform Kulit Batang Bruguiera gymnorhiza pada Sel Kanker Rahim HeLa (Apoptotic Induction by Chloroform Fraction from Stem Bark of Bruguiera gymnorhiza to the Cervix Cancer on HeLa Cells)

---

Bruguiera gymnorhiza is one of the mangrove plant that has not been widely studied as a potential anticancer. Previous research has suggested that the methanol extract of stem bark of B. gymnorhiza was cytotoxic against HeLa cells. The purpose ofthis study was to determine the cytotoxic effect and apoptosis induction of chloroform fraction from the stem bark of B. gymnorhiza on HeLa cells. The results showed that the chloroform fraction has a cytotoxic activity with IC50 of 134 µg/mL. and the double staining test indicated the presence of cells undergoing apoptosis. Based on these results, ch loro form fraction of stem bark of B. gymnorhiza is cytotoxic with the mechanism of apoptosis.
Keywords: apoptosis, Bruguiera gymnorhiza, HeLa cells, cytotoxic, chloroform fraction.

---

Availability

Detail Information

Series Title

-

Call Number

Jurnal Ilmu Kefarmasian Indonesia, 10(2) 2012 : 15

Publisher

Jakarta : FF Universitas Pancasila., 2012

Collation

5p

Language

ISBN/ISSN

1693-1831

Classification

-

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

-

Specific Detail Info

-

Statement of Responsibility

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment