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Oxygen Desaturation Index sebagai Faktor Risiko Penyakit Jantung Koroner pada Subjek Laki-laki Obstructive Sleep Apnea (Oxygen Desaturation Index as a Risk Factor for Coronary Artery Disease in Male Subject with Obstructive Sleep Apnea )
Background: Obstructive sleep apnea has been known as one of risk factor for coronary artery disease (CAD). The aim ofthis study is to examine the relation of oxygen desaturation index (ODI) due to OSA and CAD.
Methods: This study included 74 OSA men who were diagnosis of CAD by previous medical examination using treadmill and CT angiography and cardiac catheterization. Polysomnography was performed to confirm OSA diagnosis. Oxygen desaturation index was measured automatically in the polysomnogram.
Results: Of 39 subjects (ll2.7%) were diagnosed as having CAD out of 74 male OSA subjects. Cut off point ODI higherthan 11.09 showing a significant result with CAD (OR 3. 02, relative risk 75%, sensitivity 71. 79%, specificity 54.29% Likelihood ratio LR(+) 1.75, LR(-) 0.52).
Conclusion: Oxygen desaturation index may be an important contributorforCAD in OSA.
Keywords: Oxygen desaturation index, coronary artery disease, obstructive sleep apnea, male, risk factor.
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