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Fraksi Etanol 96% Biji Koro Benguk (Mucuna Pruriens L.) Sebagai Peningkat Kualitas Spermatozoa Mencit (Mus Musculus)

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Background: The examination of sperm quality is the main priority for infertility diagnosis. Based on previous study with mice, active ingredient of Mucuna pruriens L. or koro benguk (Papilionaceae), the L-dopa, may affect the quality of spermatozoa.
Objective: Research was to study the effect of 96% ethanol fraction Mucuna pruriens seed on spermatozoaquality of mice exposed to 2-Methoxy ethanol. L-dopa in 96% ethanol fraction of M. pruriens seed was 14.7%.
Methode: This was an experimental study using complete randomized design. Subjects were BALB/C mice (Mus musculus). Five groups served as control, 3 groups received subcutaneos injection of 2-ME as muchas 100 mg/kg.bw/day for 12 days, followed with 96% ethanol fraction Mucuna pruriens seed starting from14 mg/kg.bw/day, 28 mg/kg.bw/day, and 56 mg/kg.bw/day for 51 days.
Result: The 96% ethanol fraction of Mucuna pruriens seeds are significant increase motility (p

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jurnal kesehatan reproduksi 1 (2) 2011:60-66

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Jakarta : Puslitang Sistem dan Kebijakan Kesehatan., 2011

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7 p ; bibl, ilus

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ISSN: 2087-703X

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