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Katarak Diabetes

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Most of glucose solution (78%) in the lens through anaerobic glycolysis, 14% through the pentose phosphate, about 5% through the polyol. In condition sof hyperglycemia, saturated fast lane anaerobic glycolysis, and glucose will choose the path of polyol. In the polyol path glucose to sorbitol. In circumstanees where sorbitol is broken dowen into fructose by polyol dehydrogenase enzymes, but in Diabetes Mellitus polyol dehydrogenase enzyme levels low so that sorbitol accumulates in the lens of the eye. Hypertoniccondition of the aquenous liquid will atract entry into the lens of the eye, damaging the lens of architecture and place the lens opacities.

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Detail Information

Series Title

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Call Number

JKS Jurnal Kedokteran Syaigkuala: 11(1)2011:59-64

Publisher

Banda Aceh : FK. Universitas Syiah Kuala Darussalam Banda Aceh., 2011

Collation

5p.

Language

ISBN/ISSN

1412-1026

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

diabetes mellitus
cataract

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