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Pengaruh Ekstrak Rumput Laut Coklat terhadap Fungsi Sel Endotelium Aorta Tikus Diabetes (Effects of Brown Algae Extract to Function of Aorta Endothelium Cells in Diabetic Rats)

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Macro and micro vascular diseases are currently the principal causes of morbidity and mortality in diabetes mellitus patients. Loss of the modulatory role of the endothelium may be a critical and in'itiating factor in the development of diabetic vascular disease. Polyphenol is known behave protective active compound to function endothelium cell. Polyphenol that contained in brown algae was phlorotannin. The aim of the present study was to investigate the effects of S. echinocarpum extract on endothelial dysfunction in aorta of streptozotocin diabetic rats. This experiment was conducted by complete randomized design in 2 months old of male albino Sprague Dawley strain of rats, 125-150 grams body weight. The rats divided in five groups, each group consist of 6 rats. First group: normal which is given 1 mL of extract vehicle orally; second group: diabetic rats which is given 1 mL of extract vehicle orally; third

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Detail Information

Series Title

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Call Number

Majalah Farmasi Indonesia'21(3)2010:151-157

Publisher

Yogyakarta : Fakultas Farmasi UGM., 2010

Collation

6p.

Language

ISBN/ISSN

0126-1037

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

plants, medicinal
diabetes mellitus
cardiovascular diseases

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