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Penyakit Peptik dan Misorprostol

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Peptic mucus synthesize especially prostaglandine E2 and I2. Prostaglandine E2 and I2 can impede acid secete and stimulate mucus and bicarbonate secretion. Misoprostol, a synthetic methyl ester analogue of prostaglandin is both a powerful inhibitor of gastric secretion and is able to protect the gastroduodenal mucosa from damage. Misoprostol and other prostaglandine derivatives can be alternative drug of peptic ulcer relapse because the metyl ester of prostaglandin exert an antisecretion and protective effects on peptic mucus . The clinical effectiveness of misoprostol is comparable to cimethidin in short term treatment of peptic and duodenum ulcer as well as reducing duodenal ulcer relapse. Misoprostol may prevent gastrointestinal and peptic ulcer in long term treatment of Non Steroid Anti Inflamation Drug. The side effect of misorprostol is cervix naturation and uterotonic. This article describe misoprostol effectiveness on peptic and duodenum ulcer treatment.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Jurnal Kefarmasian Indonesia:1(3):105-111

Penerbit

Jakarta : Puslitbang Biomedis dan Farmasi Badan Litbang Kes., 2009

Deskripsi Fisik

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Bahasa

ISBN/ISSN

2085-675X

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

peptic ulcer
PHARMAUTICAR PREPAATIONS

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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