Text

Penyakit Peptik dan Misorprostol

---

Peptic mucus synthesize especially prostaglandine E2 and I2. Prostaglandine E2 and I2 can impede acid secete and stimulate mucus and bicarbonate secretion. Misoprostol, a synthetic methyl ester analogue of prostaglandin is both a powerful inhibitor of gastric secretion and is able to protect the gastroduodenal mucosa from damage. Misoprostol and other prostaglandine derivatives can be alternative drug of peptic ulcer relapse because the metyl ester of prostaglandin exert an antisecretion and protective effects on peptic mucus . The clinical effectiveness of misoprostol is comparable to cimethidin in short term treatment of peptic and duodenum ulcer as well as reducing duodenal ulcer relapse. Misoprostol may prevent gastrointestinal and peptic ulcer in long term treatment of Non Steroid Anti Inflamation Drug. The side effect of misorprostol is cervix naturation and uterotonic. This article describe misoprostol effectiveness on peptic and duodenum ulcer treatment.

---

Availability

Detail Information

Series Title

-

Call Number

Jurnal Kefarmasian Indonesia:1(3):105-111

Publisher

Jakarta : Puslitbang Biomedis dan Farmasi Badan Litbang Kes., 2009

Collation

-

Language

ISBN/ISSN

2085-675X

Classification

-

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

peptic ulcer
PHARMAUTICAR PREPAATIONS

Specific Detail Info

-

Statement of Responsibility

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment