Efek Paparan Glukosa Konsentrasi Tinggi terhadap Peningkatan Aktivitas Isozin Protein Kinase C (PKC)-Alpha pada Kultur sel Stroma Prostat | Perpustakaan Badan Kebijakan Pembangunan Kesehatan

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Efek Paparan Glukosa Konsentrasi Tinggi terhadap Peningkatan Aktivitas Isozin Protein Kinase C (PKC)-Alpha pada Kultur sel Stroma Prostat

Basuki B. Purnomo - Personal Name; I Wayan Widharse - Personal Name; Aulani'am - Personal Name;

To prove that glucose treatment in human prostatic stromal cells (GPSC) culture wound increase PKC alpha isozyme activity. Primary cuktures of HPSC were obtained from patients with blader outlet obstruction caused by benign prostatic enlargement. The effects various contrations of glucose (5,10.15.20.30.35 micro-Mol) on PKC-alpha isozyme activity were examined quantitatively by spectropotometry method. Spectrophotometry analysis, which is used to assess isozyme activity quantitatively showed that exposures to various doses of glucose resultted in increased isozyme activity. The increment of activity is linear with the incement of glucose dose. There is a strong correlation between gulcose doses and PKC-alpha activity wit R² = 0.91. At different concentration glucoses PKC-alpha isozyme activity of HPSC.

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Location name is not set Jurnal Urologi Indonesia: 16(1):1-5

A00002819

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Series Title: -
Call Number: Jurnal Urologi Indonesia: 16(1):1-5
Publisher: Surabaya : Ikatan Ahli Urologi Indonesia., 2009
Collation: -
Language
ISBN/ISSN: 0853-4438
Classification: -
Content Type: -
Media Type: -
Carrier Type: -
Edition: -
Subject(s): prostatic hypertrophy
urinary tract infections
PROTEIN KINASE C
STROMAL CELLS
Specific Detail Info: -
Statement of Responsibility: -

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