To prove that glucose treatment in human prostatic stromal cells (GPSC) culture wound increase PKC alpha isozyme activity. Primary cuktures of HPSC were obtained from patients with blader outlet obstruction caused by benign prostatic enlargement. The effects various contrations of glucose (5,10.15.20.30.35 micro-Mol) on PKC-alpha isozyme activity were examined quantitatively by spectropotometry…