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Determining of Delayed Gastric Emptying with Sintigraphy on Diabetes Mellitus Patient (Waktu Pengosongan Lambung Diukur Secara Sintigrafi pada Penderita Diabetes Mellitus)

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Delayed gastric emptying known as gastroparesis is a form of autonomic neuropathy, a complication of diabetes mellitus. This delay may lead to a discrepancy between intestinal food absorption and insulin or oral and diabetes drugs action. Thus it can cause difficulty in controlling a blood glucose level. In determining the existence of a delayed gastric emptying we cannot depend only the clinical signs and gastric symptoms but we need to perform on objective examination. Up to now it is known that the most reliable method for the examination is the scintigraphy. Based on the above consideration, a study was conducted to analyze the pattern of the gastric emptying time in diabetic patients with and without gastric complaints, and to differenciate between the two groups, scintigraphically. The approach to the problem it this study is medical, through a comparative prospective method with sampling from consecutive admission. The sampling units were sixteen diabetic patients, decided in two groups : 8 with gastric complaints and 8 without gastric complaints, and was attended from the out patient department of Endocrinology sub-division, department of Internal Medicine Hasan Sadikin Hospital Bandung, between October 1991 and February 1992. The gastric emptying time was determined by measuring the emptying half-time (t 1/2) after investigation of a Tc-99m labelled solid test meal. A 't-student approach' was used as statistical analysis to evaluate of at 1/2 between the two groups. The results show that the mean t 1/2 of the group with symptoms was symptoms was 1127, SD 7.3 minutes, range 101.1-121.7 minutes, and the mean t 1/2 of the group without symptoms was 100.3, SD 17.6 minutes, range 78.2-123.8 minutes. The analysis showed that mean of t 1/2 of group with symptoms was significantly longer than the other group (t'=1.83, p less than 0.05) although there were cases among in the group without symptoms who had a longer t 1/2 than that of the group with symptoms. This study that the possibility of gastric emptying delay will be found more often in patient with gastric symptoms than patient without gastric symptoms. Although gastric symptoms is not always paralel with prolongation gastric emptying time. A suggestion that could be carried out from this study is that the examination of gastric emptying should be performed on diabetic patients with gastric symptoms or on diabetic patients without gastric symptoms but with difficulties in blood glucose control.

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Majalah Kedokteran Bandung,27(1)1995:1-8

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: ., 1995

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diabetes mellitus
gastric emptying

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