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The Effective of Rivanol Tampon Compared With Burowi Tampon in Acute Diffuse Otitis Externa

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Acute diffuse otitis externa (ADOE) is one the common diseases in ENT Department, Dr. Sardjito Hospital, with the frequency of 9-12%. The most common microorganism found is Pseudomonas aeruginosa. Infection usually occurs after taking a bath, washing hair, and scratching the external ear canal. Treatment of acute diffuse otitis externa which consists to topical preparations, i.e. antibiotics and antinflammation tampon or ear drop, is relatively expensive. A rationale, high recovery rate, cheap easly found preparation is needed. Burowi solution is one of the recommended treatment, but it is less popular. The goal of this study was to know the effectiveness of Rivanol tampon compared with Burowi tampon in acute diffuse otitis externa. A randomized single-blind controlled trial (RCT) was performed at the outpatient clinic of ENT Department of Dr Sardjito General Hospital, Yogyakarta. Sixty-five subjects who were diagnosed as ADOE who met inclusion criteria were randomly allocated into two groups, that is, Rivanol group and Burowi group. The ear canal was cleaned, and then Rivanol tampon or burowi tampon was applied. Evaluation was performed on day 3 and 5. Primary outcome was the recovery rate, and secondary outcomes were adverse and marginal cost-effectiveness. Of 65 subjects, 33 were allocated into Rivanol group and 32 were allocated into Burowi group. The recovery rate in Rivanol group was 75.4%, while in Burowi groups was 49.3%. The diference in recovery rate between the two groups was statistically significant (p:0.018; RR 4.350; 95% Ci 1.225-15.442). Adverse reaction in Rivanol group was dampness and soggy feeling in the ear canal (1.5%), while in the Burowi group the adverse events were pain and burnt sensation in the ear canal (3.1%), but they could be tolerated and disappeared on day 5. Analysis on marginal cost-effectiveness showed that the cost to cure one acute diffuse otitis externa patient wit Rivanol tampon was Rp 1.000. Rivanol tampon was more clinically effective and more cost-effective than Burowi tampon for acute diffuse otitis externa treatment.

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Detail Information

Series Title

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Call Number

Berkala Ilmu Kedokteran, 41(3): 157-163

Publisher

Yogyakarta : FK. Universitas Gadjah Mada., 2009

Collation

7p.

Language

English

ISBN/ISSN

0126-1312

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

OTITIS EXTERNA

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