Acute diffuse otitis externa (ADOE) is one the common diseases in ENT Department, Dr. Sardjito Hospital, with the frequency of 9-12%. The most common microorganism found is Pseudomonas aeruginosa. Infection usually occurs after taking a bath, washing hair, and scratching the external ear canal. Treatment of acute diffuse otitis externa which consists to topical preparations, i.e. antibiotics a…