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The Comparison of Hydration Effect of 1% Aloe Vera Extract Cream and 10% Urea Cream As Moisturized for Non Dermatotic Skin
Xerotic or dry skin is a condition with manifestation of scaly, coarse skin with itchy sensation. Moisturizers have been used as treatment to alleviate xerotic skin. Aloe vera is a traditional medicinal plant which has been as skin monisturized for a long time, however, the hydration effect of this material had not been studied. Urea is a humectants material that has been widely used as moisturizer. This study was aimed to compare the hydration effects of 1% Aloe vera extract cream with 10% urea cream as moisturizer for non-dermatotic dry skin. This research was s single-blinded randomized controlled trial. Thirty research subjects who met inclusion criteria were give 2 types of interventions (1% Aloe vera extract cream or 10% urea cream). Randomization was conducted to determine which cream was applied on the subject’s lower arm. Cream was given as a single application. Evaluation of stratum corneum hydration level was conducted objectively using corneometer instrument: before application, 30 minutes, 1 hours, 2 hours, 3 hours and 4 hours after single application. Data of the two groups were analyzed with paired t-test. There was no significant difference of stratum corneum hydration level between 1% Aloe vera extract cream treatment and 10% urea cream at each time of measurement (p>0.05). 1% Aloe vera extract cream showed similar or equivalent hydration effect with 10% urea cream as moisturizer for non-dermatotic dry skin
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