Wrinkles is caused by a decreased by a decrease in collagen synthesis an incease in collagen degradation. Collagen synthesis depends on fibroblast proliferation. Collagen synthesis needs glucose, so that collagen synthesis may be expressed by the increase in glucose uptake. Skin rejuvenation with heating may increase the collagen synthesis. The effect of short-term heating and optimal temperatu…
Xerotic or dry skin is a condition with manifestation of scaly, coarse skin with itchy sensation. Moisturizers have been used as treatment to alleviate xerotic skin. Aloe vera is a traditional medicinal plant which has been as skin monisturized for a long time, however, the hydration effect of this material had not been studied. Urea is a humectants material that has been widely used as moistur…