Text
The Efficacy of the combination of 2% Lidocaine and 0.5% Bupivacaine as Preemptive Analgesia for Post-Operative Pain in Vitrectomy With or Without Scleral Buckle Under General Anaesthesia
Post-operative pain is one of the main problem in the surgical services so that analgesia is very much needed, even intravenously given. The concept of preemptive analgesia surgical intervention is the provision of analgesia before the accurence of nociceptive stimulus. One of the agents for providing preemptive analgesia is local injection is local injection with local anesthetic, single or in combination. Preemptive analgesia is local injection is local injection with local anesthetic, single or in combination. This study was aimed to evaluate efficacy of combination of lidocain and bupivacain as preemptive analgesia in vitrectomy with or without sclera buckle under general anesthesia. Twenty eight patients who were scheduled for vitrectomy were included in this study. The patients were randomly classified into equal groups . The surgery was conducted under general anesthesia for both groups, but in Group 1, subtenon anesthesia with local anesthetic was given as preemptive analgesia after induction anesthesia and before the start of sugery. Pain intensity was measured in 3 hours and 24 hours after surgical procedure. The baseline characteristics between the two groups were similar. The pain intensity was lower in the treatment group, but the difference was not statiscally significant (1.00±1.71 vs 1.50±2.16, p=0.109). The proportion of pain-free patients were similar between the two groups in 3 hours after procedure (65% vs 65%, p = 1.00). The proportion of pain-free patients were higher in the treatment group in 24 hours after procedure (100% vs 73%, p = 0.222. Fisher’s Exact Test). The subtenon injection procedure was safe. There was insignificant difference in the incidence of side effects of side effects between the 2 groups. This study did not show any additional benefit of subtenon injection for vitrectomy. The pain intensity was similar between two groups. There were on side effects after the procedure.
No other version available