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Temu kunci (Boesenbergia pandurata) rhizome showed cytotoxic effect against T47D breast cancer cell line. It contains Panduratin, a chalcone compund, that has been investigated as chemopreventive agent. The exploration of extract of temu kuci as chemopreventive agent was expected to be an alternative for cancer therapy. The aim of this research was to determine the cytotoxic activities of ethan…
Cerumen obturans is a pahtological condition with no harmfull to the patients but can caused ear tumbness sensation, earache, hearing impairment, deafness and decreasing the quality of life.The objections of the study are to compare the effectivity of six solvents, that are aquadest, NaCl 0,9%, coconut oil, olive oil, carboglycerin 10% and sodium docusate 0,5% againts cerumen obturans by means …
Medication eror adalahkejadian yang menggunakan pasien akibat penanganan yang dilakukan oleh tenaga kesehatan (human error) yang sebetulnya dapat dicegah Medication error dapat diklasifikasi menjadi dispensing errors and administration erroes. Penyebab ledication error antara lain komunikasi yang kurang bai, baban kerja sistem distribusi dan peran tenaga farmasi belum maksimal. Telah dilakukan …
Apoptosis is known to maintenance of tissue homeostasis and elimination of cancer cells. Whithout programed cell death, cell proliferation would lack on important component of control of oncogenic process. Apoptosis is caused by various inducers such as chemival compound and toxin. Aflatoxin B1 is a potent toxin. In the liver, it undergoes biotransformation which produces reactive oxigen specie…
Oxidative stress has been implicated in pathogenesis of diabetes mellitus. In addition to increased production of free radicals, antioxidant defense systems are disturbed in diabetes mellitus. As a result, oxidative stress may cause oxidative damage of B-cell pancreas. Hydnophytum formicarum consists of flavonoid which function as an antioxidant. So that, it necessary do research to know influe…
One of the natural materials as potentially efficacious chemopreventive agents are Ciplukan (Physalis angulata L.). Several previous studies reported that Physalis angulata L. herbs ethanolic extract (PEE) has cytotoxic activity and induction of apoptosis in breast cancer cells MCF-7 and HeLa cervical cancer cells. This study aims to determine the effects of PEE as an chemopreventive agent on …
Sarang semut (Myrmecodia pendans) is an Indonesian native plant that has been used in folk medicine. Researches showed sarang semut has antioxidant effect, xantinoxidase inhibitor potency, and anticancer activity. The efficacy and safety of this plant should have been proven before used in modern medicine. The objective of this research was to assess the potency of acute toxicity, evaluate tox…
Pada tahun-tahun terakhir ini beberapa air sungai di wilayah Kalimantan Timur dilaporkan telah tercemar oleh logamberat jenis merkuri(Hg). Sungai salah satu sumber air baku PDAM, selain itu sungai juga dipergunakan untuk keperluan sehari-hari seperti mandi, cuci dan masak. Hasil pantauan Badan Lingkungan Hidup daerah Kabupaten Kutai Kartanegara pada air baku, daeah aliran sungai, sedimen (lumpu…
Menurut laporan WHO tahun 1999, mellaporkan bahwa di Prancis pernah terjadi 8 kasus pekerja kesehatan terinfeksi HIV melalui luka 2 kasus diantaranya menimpa petugas yang menangani limbah medis Pemakaian alat suntik setiap bulan untuk pengobatan mencapai 10 juta pelayanan padahan selain untuk pengobatan alat suntik juga digunakan dalam program imunisasi bagi bayi dan anak-anak yang setiap tahu…
Beban cedera makin meningkat sehingga dibutuhkan penyediaan dan penyajian data yang cepat dan terbaru. Sistem dokumentasi data cedera dari berbagai sumber masih bersifat manual sehingga pemanfaatan data kurang optimal. Diperlukan model sistem registri data dasar trauma yang sederhana, aplikatif, informatif dan mudah diakses oleh pengguna sebagai penunjang sistem surveilans cedera. Penelitian in…