ABSTRACT Hiperthyroid is execcesive thyroid function which increased thyroid hormone that suppressed TSH. Majoretiologies of hyperthyroidism (60%-80%) caused by Graves disease. Graves disease occurs in up to 2% women 20-40 years old. Some of the genes implicated in this pathogenesis may encode thyroid stimulating hormones receptors (TSHR). The TSHR gene is located on chromosome 14q31, an area …
Abstract Objectives: To determine the factors that may be used as the prog¬nostic parameter for the therapeutic efficacy of neoadjuvant chemo¬therapy, which can be used to revising the management of early stage cervical cancer patients with large lesions. Methods: This was a retrospective cohort study. The study was con¬ducted in the Dr. Cipto Mangunkusumo Hospital, Faculty of Medi¬cine…
ABSTRACT Free radicals are formed in the body as a by-product of an aerobic respiration. During pregnancy, the increase in free radicals potentially causes structural and functional damages to fetus. Tempeh is originally from Indonesia having various nutrition inclding vitamin, mineral and isoflaphon serving as antioxidhant having potential to reduce and improve DNA damage. This study was aime…
Abstract Introduction: The aim of this study was to assess the process and outcome of the Faculty of Medicine, University of Indonesia (FMUI)'s education in the management of pregnant and deliv¬ering mother; as well as neonates. Methods: Cross sectional study that asses process and education outcome in Faculty of Medicine, University of Indonesia's students who went through and finished wo…
Abstract Background: Low Birth Weight (
Iodine deficiency lowers circulating thyroxine (T4) and raises serum Thyroid Stimulating Hormone (TSH), where free T4 (fT4) and TSH have strong corelation with thyroglobulin (Tg). The results from population studies indicate, Tg appears to be a valuable indicator of thyroid status, but it has yet to be fully explored. This study aimed to measure the association between serum Tg with TSH and fT4…
Corynebacterium diphtheriae is the causative agent of diphtheria. The main virulence determinant of the bacteria is diphtheria toxin, the cause of the systemic complication seen with diphtheria. Production of diphtheria toxin by toxigenic strain encoded by dtx/tox gene and repressed by dtxR gene. Gold standard for bacterial toxigenicity test carried out by conventional methods (Elek test, Guine…
The identification of a point mutation in voltage-gated sodium channel gene was conducted on the major of dengue vector Aedes aegypti from Simongan Village, Semarang Municypality Central Java, which occurred to be resistant toward malathion and cypermethrin base on WHO methodology standard (impregnated paper). The objectives of this studi was to identify the point mutation on the codon 1014 o…
Anemia merupakan salah satu dampak infeksi malaria falsiparum dan malaria vivaks. Respon imun ternyata mempengaruhi kadar hemoglobin. Sitokin proinflamasi dan antiinflamasi memainkan peranan penting terjadinya anemia penderita terinfeksi P. falciparum dan P. Vivax.Tujuan penelitian adalah untuk menilai hubungan antara kadar hemoglobin dengan sitokin TNFα, IFNγ, IL12 dan IL10 pada penderita ma…