Sambiloto (Andrographis paniculata Nees) is a medicinal plant containing andrographolide as its pri mary bioactive component, which has been shown to inhibit breast cancer cell proliferation. Andrographolide is a diterpene lacton and sparingly soluble in water. The aim ofthis study is to prepare microspheres of A. paniculata ethylacetate fraction by microencapsulation using spray drying method.…